Sodium Phosphate Monobasic

Sodium phosphate monobasic is used in varied lab experiments and is a chemical that is also important to your body. At room temperature it is a white solid powder and works as a buffering solution in unison with sodium phosphate dibasic, where controlling rapid ph fluctuations both in lab experiments and in your body. Although it can be toxic when combined with other drugs, solutions of sodium phosphate can help relieve constipation symptoms.

The chemcial formula for sodium phosphate monobasic is NaH2PO4 which is a combination of 1 sodium or Na atom, 2 hydrogen or H atoms and 1 phosphate or P04 group. There is also the monohydrate form, NAH2PO4+H2O, where 1 water or H2O molecule is associated with with each sodium phosphate monobasic molecule. Monobasic term is referred to single or univalent base group neutralizing the molecule. Whereas, the sodium phospate dibasic form (Na2HPO4 +2H20), when dissolved, dissociates into 2 sodium atoms requiring to be neutralized by 2 basic groups.

Sodium phosphate monobasic is slightly acidic and has a ph of 4.5 It exists as an odorless, white crystalline powder. The H2PO4 dissociated group only requires 1 hydrogen in neutralizing the molecule since it only has 1 negative net negative charge. In comparison, the sodium phosphate dibasic form has a higher level of ph (9.5) because there is a net negative charge of 2 from the dissociated HPO4 group, whereby the group requiring more acid for neutralization. Sodium phosphate monobasic melts at 212 degrees F and boils at 399 degrees F.

As a buffering agent, sodium phosphate monobasic when challenged by a base or acid, prevents the ph of the solution to change. In all cellular fluids exist sodium phosphate buffers. H2PO4- or dihydrogen phospate ions are acting as acids while HPO4 or hydrogen phosphate are acting as bases. Both these ions keep cellular fluids in a close ph range of 6.9 to 7.4 and are in equilibrium.

When sodium phosphate monobasic is combined with sodium phosphate dibasic, it induces bowel movements by acting as a laxative. This combination, as a pharmaceutical agent, helps constipation or prior to surgery, colonoscopy or other medical procedures in emptying the bowels. This medication’s side effects can potentially include dizziness, allergic reactions, fainting, seizures, dry mouth, irregular heart rhythm, decreased urination, nausea, severe stomach pain, bloating, vomiting and red or black stools.

Sodium phosphate monobasic as a pure chemical is irritating to the eyes, skin and respiratory tract and if inhaled or swallowed can be harmful. Without consulting a health professional, phosphate buffer laxatives shouldn’t be mixed with other medicines. Bad reactions could result if taking in combination with drugs tailored to treat depression, lower blood pressure or pain management, or if having heart, kidney, electrolyte problems, a history of seizures or if pregnant or breastfeeding.

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